Duke vs. Clemson Prediction: Duke Predicted to Win College Basketball Matchup [2/8/2025]

Clemson will face the favored Duke in college basketball action at Littlejohn Coliseum on Saturday, beginning at 6:30PM ET.

Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Duke as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Duke-Clemson game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Duke is more likely to win, while Clemson has a lower chance of victory."

For further insights into Saturday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Duke vs. Clemson predictions page.

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Duke vs. Clemson Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball game between Duke and Clemson 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model currently gives Duke a 74% chance of defeating Clemson. Our predicted final score has Duke winning 72-66.

According to our model, Clemson (+6.5) has a 51% chance of covering the spread, while the over/under total of 135 points has a 55% chance of going over.

Duke vs. Clemson Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

Bet Type	Duke	Clemson
Spread	-6.5 (-102)	+6.5 (-110)
Moneyline	-265	+220
Total	o135 (-110)	u135 (-110)

All odds are correct at the time of publication and are subject to change.

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Duke vs. Clemson Picks and Best Bets

Our model's strongest edge in today's Duke vs. Clemson matchup is on the spread.

Our expert predictions, aligned with the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Duke vs. Clemson Game-Day Updates and Essential Details

Saturday's college basketball action between Clemson and Duke at Littlejohn Coliseum is scheduled to start at 6:30PM ET.

• Who: Duke vs. Clemson
• Date: Saturday, February 8, 2025
• Time: 6:30PM ET/3:30PM PT
• Venue: Littlejohn Coliseum

Dimers.com's in-depth preview of Saturday's Duke vs. Clemson matchup includes our prediction, picks and the latest betting odds.

Before making any Duke vs. Clemson picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Conclusion

We predict Duke, with a 74% win probability, will likely beat Clemson on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Duke vs. Clemson insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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