Drake vs. South Dakota State prediction: South Dakota State favored to win in college football Week 3, 2025

South Dakota State and Drake will meet in Week 3 college football action at Dana J. Dykhouse Stadium on Saturday, with kickoff at 7:00PM ET.

Based on the latest simulations, Dimers' proven college football model projects South Dakota State as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Drake vs. South Dakota State predictions page.

Drake vs. South Dakota State prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the result of Drake vs. South Dakota State 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives South Dakota State a 99% chance of defeating Drake. Our predicted final score has South Dakota State winning 40-7.

According to our model, the bookmakers have got it right, and Drake and South Dakota State each have a 50% chance of covering the spread, while the 48.5-point over/under also has an equal 50-50 chance of hitting.

Drake vs. South Dakota State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Drake	South Dakota State
Spread	+34.5 (-105)	-34.5 (-115)
Moneyline	+5500	-50000
Total	o48.5 (-110)	u48.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Drake vs. South Dakota State picks and best bets

Our model's biggest edge in today's Drake vs. South Dakota State matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Drake vs. South Dakota State game-day updates and essential details

Saturday's college football game between South Dakota State and Drake at Dana J. Dykhouse Stadium is scheduled to commence at 7:00PM ET.

• Who: Drake vs. South Dakota State
• Date: Saturday, September 13, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Dana J. Dykhouse Stadium

Dimers' comprehensive preview of Saturday's Drake vs. South Dakota State matchup includes our prediction, picks and the latest betting odds.

Before making any Drake vs. South Dakota State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict South Dakota State, with a 99% win probability, will likely beat Drake on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Drake vs. South Dakota State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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