Tigers vs. Yankees prediction: Yankees favored to win Wednesday's MLB matchup [9/10/2025]

The New York Yankees will square off with the Detroit Tigers in MLB action at Yankee Stadium on Wednesday, beginning at 7:05PM ET.

The Yankees will send Carlos Rodón (16-7, 3.12 ERA) to the mound, up against Jack Flaherty (7-13, 4.85 ERA) for the Tigers.

Based on the latest simulations, Dimers' advanced MLB model projects the Yankees as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Tigers-Yankees game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Yankees' chance of winning at 63%, with the Tigers at 37%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Tigers vs. Yankees predictions page.

Yankees vs. Tigers prediction: Who will win, cover the run line?

Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's MLB game between the Tigers and Yankees 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Yankees a 63% chance of beating the Tigers.

According to our model, the Tigers (+1.5) have a 56% chance of covering the run line, while the over/under total of 8 runs has a 55% chance of going over.

Tigers vs. Yankees odds [9/10/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Tigers	Yankees
Run Line	+1.5 (-140)	-1.5 (+120)
Moneyline	+145	-172
Total	o8 (-115)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Tigers vs. Yankees picks and best bets

Our model's biggest edge in today's Tigers vs. Yankees matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Tigers vs. Yankees game-day updates and essential details

Wednesday's MLB action between the Yankees and Tigers at Yankee Stadium is scheduled to start at 7:05PM ET.

• Who: Detroit Tigers vs. New York Yankees
• Date: Wednesday, September 10, 2025
• Time: 7:05PM ET/4:05PM PT
• Venue: Yankee Stadium

Dimers' in-depth preview of Wednesday's Tigers vs. Yankees matchup includes our prediction, picks and the latest betting odds.

Before making any Tigers vs. Yankees picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Yankees, with a 63% win probability, will likely beat the Tigers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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