Tigers vs. Twins prediction: Minnesota predicted to win Saturday's MLB matchup [8/16/2025]

MLB action continues on Saturday at 7:15PM ET as the Detroit Tigers take on the Minnesota Twins at Target Field.

Zebby Matthews (3-4, 5.11 ERA) will get the ball for the Twins, pitting him against Casey Mize (11-4, 3.50 ERA) for the Tigers.

Based on updated simulations, Dimers' proven MLB model projects the Twins as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Tigers vs. Twins predictions page.

Twins vs. Tigers prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Tigers and Twins 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Twins a 51% chance of defeating the Tigers.

According to our model, the Tigers (+1.5) have a 67% chance of covering the run line, while the 9-run over/under has an equal 50-50 chance of hitting.

Tigers vs. Twins odds [8/16/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Tigers	Twins
Run Line	+1.5 (-225)	-1.5 (+175)
Moneyline	-106	-108
Total	o9 (+100)	u9 (-122)

All odds are correct at the time of publication and are subject to change.

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Tigers vs. Twins picks and best bets

Our model's biggest edge in today's Tigers vs. Twins matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

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Tigers vs. Twins game-day updates and essential details

Saturday's MLB matchup between the Twins and Tigers at Target Field is scheduled to begin at 7:15PM ET.

• Who: Detroit Tigers vs. Minnesota Twins
• Date: Saturday, August 16, 2025
• Time: 7:15PM ET/4:15PM PT
• Venue: Target Field

Dimers.com's in-depth preview of Saturday's Tigers vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any Tigers vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Twins, with a 51% win probability, will likely beat the Tigers on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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