Tigers vs. Astros Prediction: Houston Predicted to Win Monday's MLB Matchup [4/28/2025]

The Houston Astros will take on the Detroit Tigers, in what is expected to be a close MLB game, at Daikin Park on Monday, beginning at 8:10PM ET.

Ronel Blanco (2-2, 5.01 ERA) will start on the mound for the Astros, up against Jack Flaherty (1-2, 2.63 ERA) for the Tigers.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Detroit-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Astros are likely to win, with a probability of 52%, compared to the Tigers' 48%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Tigers vs. Astros predictions page.

Astros vs. Tigers Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Monday's MLB game between the Tigers and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 52% chance of defeating the Tigers.

According to our model, the Astros (+1.5) have a 65% chance of covering the run line, while the 7.5-run over/under has a 52% chance of going over.

Tigers vs. Astros Odds [4/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Tigers	Astros
Run Line	-1.5 (+172)	+1.5 (-205)
Moneyline	+102	-118
Total	o7.5 (+102)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Tigers vs. Astros Picks and Best Bets

Our model's biggest edge in today's Tigers vs. Astros matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Tigers vs. Astros Game-Day Updates and Essential Details

Monday's MLB action between the Astros and Tigers at Daikin Park is scheduled to begin at 8:10PM ET.

• Who: Detroit Tigers vs. Houston Astros
• Date: Monday, April 28, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Monday's Tigers vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Detroit vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 52% win probability, will likely beat the Tigers on Monday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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