Tigers vs. White Sox Prediction: Detroit Predicted to Win Wednesday's MLB Matchup [8/13/2025]

The Chicago White Sox will face the Detroit Tigers in MLB action at Rate Field on Wednesday, starting at 2:10PM ET.

The White Sox will send Shane Smith (3-7, 4.22 ERA) to the mound, pitting him against Troy Melton (2-1, 3.64 ERA) for the Tigers.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Tigers as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Tigers-White Sox game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Tigers' chance of winning at 55%, with the White Sox at 45%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Tigers vs. White Sox predictions page.

White Sox vs. Tigers Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's MLB game between the Tigers and White Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Tigers a 55% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 59% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.

Tigers vs. White Sox Odds [8/13/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Tigers	White Sox
Run Line	-1.5 (+118)	+1.5 (-135)
Moneyline	-145	+126
Total	o8 (-114)	u8 (-102)

All odds are correct at the time of publication and are subject to change.

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Tigers vs. White Sox Picks and Best Bets

Our model's strongest edge in today's Tigers vs. White Sox matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Tigers vs. White Sox Game-Day Updates and Essential Details

Wednesday's MLB game between the White Sox and Tigers at Rate Field is scheduled to begin at 2:10PM ET.

• Who: Detroit Tigers vs. Chicago White Sox
• Date: Wednesday, August 13, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Rate Field

Dimers.com's comprehensive preview of Wednesday's Tigers vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Tigers vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Tigers, with a 55% win probability, will likely beat the White Sox on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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