Tigers vs. Red Sox prediction: Boston favored to win Saturday's MLB matchup [9/27/2025]

The Boston Red Sox will take on the Detroit Tigers in MLB action at Fenway Park on Saturday, commencing at 4:10PM ET.

Connelly Early (1-1, 1.88 ERA) will be on the bump for the Red Sox, up against Keider Montero (5-3, 4.48 ERA) for the Tigers.

Based on updated simulations, Dimers' proven MLB model predicts the Red Sox as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Tigers vs. Red Sox predictions page.

Red Sox vs. Tigers prediction: Who will win?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Saturday's MLB matchup between the Tigers and Red Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Red Sox a 56% chance of beating the Tigers.

According to our model, the over/under total of 8.5 runs has a 60% chance of going over.

Tigers vs. Red Sox odds [9/27/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Tigers	Red Sox
Moneyline	+100	-116
Total	o8.5 (-110)	u8.5 (-106)

All odds are correct at the time of publication and are subject to change.

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Tigers vs. Red Sox picks and best bets

Our model's strongest edge in today's Tigers vs. Red Sox matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Tigers vs. Red Sox game-day updates and essential details

Saturday's MLB matchup between the Red Sox and Tigers at Fenway Park is scheduled to start at 4:10PM ET.

• Who: Detroit Tigers vs. Boston Red Sox
• Date: Saturday, September 27, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Fenway Park

Dimers' in-depth preview of Saturday's Tigers vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Tigers vs. Red Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Red Sox, with a 56% win probability, will likely beat the Tigers on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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