Lions vs. Packers prediction: Green Bay favored to win in NFL Week 1, 2025

The Green Bay Packers will face the Detroit Lions in NFL Week 1 action at Lambeau Field on Sunday, starting at 4:25PM ET.

Based on updated simulation results, Dimers' proven NFL model projects the Packers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Lions-Packers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Packers with a win probability of 55%, while the Lions have 45%."

This updated Lions vs. Packers betting preview builds on my Lions vs. Packers prediction that was posted earlier in the week.

For further insights into today’s game, including the predicted score, best bets and player prop picks, visit our interactive Lions vs. Packers predictions page.

Lions vs. Packers Predictions

Since our Lions-Packers predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Lions and Packers 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Packers a 55% chance of defeating the Lions in Week 1 of the NFL season. Our predicted final score has the Packers winning 24-23.

According to our model, the bookmakers have got it right, and the Lions and Packers each have a 50% chance of covering the spread, while the over/under total of 48 points has a 53% chance of going over.

Lions vs. Packers odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type	Lions	Packers
Spread	+1.5 (-110)	-1.5 (-105)
Moneyline	+100	-115
Total	o48 (-110)	u48 (-110)

All odds are correct at the time of publication and are subject to change.

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Lions vs. Packers picks and best bets

Our model's biggest edge in today's Lions vs. Packers matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best NFL picks and NFL best bets for every game throughout the season, with today's best NFL bets populating now.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Lions vs. Packers TD scorers

Who will score an anytime touchdown in Lions vs. Packers?

According to our list of touchdown scorer predictions for Week 1, Green Bay's Josh Jacobs is most likely to score the first TD in Lions vs. Packers.

Our projections give Jacobs a 13.6% chance of scoring the first TD at Lambeau Field, while the Packers running back is a 55.4% chance of scoring an anytime touchdown.

First touchdown scorer predictions

Detroit Lions

Player	First TD Probability
Jahmyr Gibbs (RB)	12.3%
David Montgomery (RB)	9.3%
Amon-Ra St. Brown (WR)	7.2%

Green Bay Packers

Player	First TD Probability
Josh Jacobs (RB)	13.6%
Matthew Golden (WR)	5.0%
Tucker Kraft (TE)	4.9%

Anytime touchdown scorer predictions

Detroit Lions

Player	Anytime TD Probability
Jahmyr Gibbs (RB)	55.8%
David Montgomery (RB)	45.8%
Amon-Ra St. Brown (WR)	37.9%

Green Bay Packers

Player	Anytime TD Probability
Josh Jacobs (RB)	55.4%
Matthew Golden (WR)	25.7%
Tucker Kraft (TE)	25.4%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 1 touchdown scorer predictions

Lions vs Packers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Lions and Packers. For more, check out today's highest-probability NFL prop bets.

Already a Dimers Pro member? Head to our Lions-Packers page now to access every player prop projection.

Lions vs. Packers quarterbacks

Of the starting quarterbacks, the Lions' Jared Goff is projected to throw for more yards than the Packers' Jordan Love.

Lions rushing

Jahmyr Gibbs, David Montgomery and Jameson Williams are projected to be the leading rushers for the Lions.

Player	Position
Jahmyr Gibbs	RB
David Montgomery	RB
Jameson Williams	WR

Packers rushing

Josh Jacobs, Emanuel Wilson and Chris Brooks are expected to lead the Packers in rushing yards.

Player	Position
Josh Jacobs	RB
Emanuel Wilson	RB
Chris Brooks	RB

Lions receiving

Amon-Ra St. Brown, Jameson Williams, Sam LaPorta, Jahmyr Gibbs and Isaac TeSlaa are projected to top the receiving yards for the Lions.

Player	Position
Amon-Ra St. Brown	WR
Jameson Williams	WR
Sam LaPorta	TE
Jahmyr Gibbs	RB
Isaac TeSlaa	WR

Packers receiving

Matthew Golden, Romeo Doubs, Tucker Kraft, Jayden Reed and Dontayvion Wicks are projected to lead the Packers in receiving yards.

Player	Position
Matthew Golden	WR
Romeo Doubs	WR
Tucker Kraft	TE
Jayden Reed	WR
Dontayvion Wicks	WR

Lions vs. Packers game-day updates and essential details

The NFL Week 1 game between the Packers and Lions at Lambeau Field is scheduled to commence at 4:25PM ET.

• Who: Detroit Lions vs. Green Bay Packers
• Date: Sunday, September 7, 2025
• Time: 4:25PM ET/1:25PM PT
• Venue: Lambeau Field

Dimers.com's full preview of this week's Lions vs. Packers matchup includes our prediction, picks and the latest betting odds.

Before making any Lions vs. Packers picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Packers, with a 55% win probability, will likely beat the Lions in Week 1 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Lions vs. Packers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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