Detroit Lions vs. Baltimore Ravens early prediction: Expert picks for NFL Week 3, 2025

The Detroit Lions and Baltimore Ravens will meet in Week 3 of the NFL season at M&T Bank Stadium on Monday, September 22, 2025, starting at 8:15PM ET.

Initial simulations from Dimers' trusted NFL model favor the Ravens as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Lions vs. Ravens predictions page.

Detroit vs. Baltimore early predictions

Leveraging trusted machine learning and analysis, we have simulated the Lions vs. Ravens game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Lions 39%, Ravens 61%
• Predicted final score: Lions 23-26 Ravens
• Spread: Lions (+3.5) 50%, Ravens (-3.5) 50%
• Total points (49.5): Over 53%, Under 47%

As of September 14, 2025, these Lions-Ravens figures and predictions reflect the latest data and insights available.

Lions vs. Ravens Week 3 details

The NFL Week 3 action between the Ravens and Lions at M&T Bank Stadium is scheduled for September 22, 2025.

• Who: Detroit Lions vs. Baltimore Ravens
• Date: Monday, September 22, 2025
• Time: 8:15PM ET/5:15PM PT
• Venue: M&T Bank Stadium

Lions vs. Ravens opening odds

We've researched the best betting odds across America for this Week 3 game, which are listed here:

• Spread: Lions +3.5 (-105), Ravens -3.5 (-115)
• Moneyline: Lions +154, Ravens -185
• Total: Over/Under 49.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Ravens, with a 61% win probability, will likely beat the Lions in Week 3 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Lions vs. Ravens matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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