Daria Kasatkina vs. Naomi Osaka prediction, odds, picks for US Open 2025

Daria Kasatkina and Naomi Osaka will lock horns in the third round of the US Open 2025 on Saturday.

Based on the latest simulation results, Dimers' advanced tennis model predicts Naomi Osaka as the most likely winner of the match.

For further insights into Saturday's match, including best bets and picks, visit our interactive Kasatkina vs. Osaka predictions page.

Kasatkina vs. Osaka prediction: Who will win and advance to the Round of 16?

Using innovative machine learning and data, we have simulated the outcome of Saturday's Kasatkina-Osaka women's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model gives Osaka a 77% chance of defeating Kasatkina in the US Open 2025.

Additionally, Osaka has a 72% chance of winning the first set, while the under 20.5 games has a 53% chance of hitting, according to our model.

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Daria Kasatkina vs. Naomi Osaka odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Kasatkina	Osaka
Moneyline	+315	-375
First Set	+220	-278
Total Games	o20.5 (-115)	u20.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Kasatkina vs. Osaka picks and best bets

Our model's biggest edge in today's Kasatkina vs. Osaka match is on the first set.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Kasatkina vs. Osaka updates and essential details

The US Open 2025 match between Daria Kasatkina and Naomi Osaka is scheduled to start on Saturday at 1:15PM ET.

• Who: Daria Kasatkina vs. Naomi Osaka
• Date: Saturday, August 30, 2025
• Approx. Time: 1:15PM ET/10:15AM PT
• Tournament: US Open Women's Singles 2025
• Round: Third round

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Saturday's Kasatkina vs. Osaka match includes our prediction, picks and the latest betting odds.

Before making any Daria Kasatkina vs. Naomi Osaka picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

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Conclusion

We predict Naomi Osaka, with a 77% win probability, will likely beat Daria Kasatkina at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Kasatkina vs. Osaka insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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