Daniil Medvedev vs. Reilly Opelka Prediction, Odds, Picks for ATP Washington Open 2025

Daniil Medvedev will face Reilly Opelka in the round of 32 at the ATP Washington event on Wednesday.

Based on updated simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Daniil Medvedev as the most likely winner of the match.

"We have simulated the outcome of Wednesday's Medvedev-Opelka match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Daniil Medvedev's chance of winning at 70%, with Reilly Opelka at 30%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Medvedev vs. Opelka predictions page.

Medvedev vs. Opelka Prediction: Who Will Win and Advance to the Round of 16?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's Medvedev-Opelka men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Medvedev a 70% chance of defeating Opelka at the ATP Washington Open tournament.

Additionally, Medvedev has a 65% chance of winning the first set, according to our model.

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Daniil Medvedev vs. Reilly Opelka Odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Medvedev	Opelka
Moneyline	-333	+250
First Set	-250	+200

All odds are correct at the time of publication and are subject to change.

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Medvedev vs. Opelka Picks and Best Bets

Our model's biggest edge in today's Medvedev vs. Opelka match is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Medvedev vs. Opelka Updates and Essential Details

The ATP Washington Open match between Daniil Medvedev and Reilly Opelka is scheduled to start on Wednesday at 12:30PM ET.

• Who: Daniil Medvedev vs. Reilly Opelka
• Date: Wednesday, July 23, 2025
• Approx. Time: 12:30PM ET/9:30AM PT
• Tournament: ATP Washington, USA Men's Singles 2025
• Round: Round of 32

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Wednesday's Medvedev vs. Opelka match includes our prediction, picks and the latest betting odds.

Before making any Daniil Medvedev vs. Reilly Opelka picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Daniil Medvedev, with a 70% win probability, will likely beat Reilly Opelka at the ATP Washington Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Medvedev vs. Opelka insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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