Cowboys vs. Eagles prediction: Why Philadelphia is favored to win TNF Week 1, 2025

The Philadelphia Eagles will take on the Dallas Cowboys in NFL Week 1 action at Lincoln Financial Field on Thursday, commencing at 8:20PM ET.

Based on updated simulations, Dimers' proven NFL model predicts the Eagles as the most likely winner of today's game.

This updated Cowboys vs. Eagles betting preview builds on my early Cowboys vs. Eagles prediction that I published at the start of the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Cowboys vs. Eagles predictions page.

Cowboys vs. Eagles Predictions

Since our Cowboys-Eagles predictions earlier in the week, we have simulated the result of Thursday's NFL game between the Cowboys and Eagles 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Eagles a 76% chance of beating the Cowboys in Week 1 of the NFL season. Our predicted final score has the Eagles winning 26-19.

According to our model, the Cowboys (+8.5) have a 52% chance of covering the spread, while the over/under total of 47.5 points has a 54% chance of staying under.

Cowboys vs. Eagles odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Cowboys	Eagles
Spread	+8.5 (-110)	-8.5 (-105)
Moneyline	+350	-420
Total	o47.5 (-110)	u47.5 (-110)

All odds are correct at the time of publication and are subject to change.

Boost your NFL betting by exploring the latest NFL betting promos, sourced from top sportsbooks and DFS operators.

Cowboys vs. Eagles picks and best bets

Our model's strongest edge in today's Cowboys vs. Eagles matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Cowboys vs. Eagles TD scorers

Who will score an anytime touchdown in Cowboys vs. Eagles?

According to our model, Philadelphia's Saquon Barkley is most likely to score the first TD in Cowboys vs. Eagles.

Our projections give Barkley a 15.3% chance of scoring the first TD at Lincoln Financial Field, while the Eagles running back is a 58.6% chance of reaching the end zone at any point in the game.

First touchdown scorer predictions

Dallas Cowboys

Player	First TD Probability
CeeDee Lamb (WR)	8.0%
Javonte Williams (RB)	7.9%
George Pickens (WR)	6.4%

Philadelphia Eagles

Player	First TD Probability
Saquon Barkley (RB)	15.3%
Jalen Hurts (QB)	14.3%
A.J. Brown (WR)	7.9%

Anytime touchdown scorer predictions

Dallas Cowboys

Player	Anytime TD Probability
CeeDee Lamb (WR)	35.0%
Javonte Williams (RB)	34.7%
George Pickens (WR)	29.4%

Philadelphia Eagles

Player	Anytime TD Probability
Saquon Barkley (RB)	58.6%
Jalen Hurts (QB)	56.0%
A.J. Brown (WR)	36.5%

Cowboys vs Eagles player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Cowboys and Eagles. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Cowboys-Eagles page now to access every player prop projection.

Cowboys vs. Eagles quarterbacks

Of the starting quarterbacks, the Cowboys' Dak Prescott is projected to throw for more yards than the Eagles' Jalen Hurts.

Cowboys rushing

Javonte Williams, Miles Sanders and Dak Prescott are projected to be the leading rushers for the Cowboys.

Player	Position
Javonte Williams	RB
Miles Sanders	RB
Dak Prescott	QB

Eagles rushing

Saquon Barkley, Jalen Hurts and Will Shipley are expected to lead the Eagles in rushing yards.

Player	Position
Saquon Barkley	RB
Jalen Hurts	QB
Will Shipley	RB

Cowboys receiving

CeeDee Lamb, George Pickens, Jake Ferguson, KaVontae Turpin and Jalen Tolbert are projected to top the receiving yards for the Cowboys.

Player	Position
CeeDee Lamb	WR
George Pickens	WR
Jake Ferguson	TE
KaVontae Turpin	WR
Jalen Tolbert	WR

Eagles receiving

A.J. Brown, DeVonta Smith, Dallas Goedert, Saquon Barkley and Jahan Dotson are projected to lead the Eagles in receiving yards.

Player	Position
A.J. Brown	WR
DeVonta Smith	WR
Dallas Goedert	TE
Saquon Barkley	RB
Jahan Dotson	WR

Cowboys vs. Eagles game-day updates and essential details

The NFL Week 1 action between the Eagles and Cowboys at Lincoln Financial Field is scheduled to start at 8:20PM ET.

• Who: Dallas Cowboys vs. Philadelphia Eagles
• Date: Thursday, September 4, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: Lincoln Financial Field

Dimers.com's full preview of this week's Cowboys vs. Eagles matchup includes our prediction, picks and the latest betting odds.

Before making any Cowboys vs. Eagles picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

NFL Week 1 betting promos and codes

Make the most of Dimers' Cowboys vs. Eagles predictions by exploring the two exciting offers below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $300 in Bonus Bets instantly plus over $200 off NFL Sunday Ticket.

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in Bonus Bets win or lose.

Sports betting deal available for Maryland sports fans

To make the most of Thursday's mammoth day of sports, headlined by this huge NFL season opener, check out details on the latest Bet365 bonus code "DIMERS" that secures $300 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict the Eagles, with a 76% win probability, will likely beat the Cowboys in Week 1 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Cowboys vs. Eagles insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Keep up with the latest NFL betting news and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date projections for the Super Bowl, AFC, NFC and each division.