Cruz Azul vs. Santos Laguna prediction, odds, Liga MX picks [8/16/2025]

Cruz Azul will take on Santos Laguna in Liga MX action at Estadio Olímpico Universitario on Saturday, commencing at 9:00PM ET.

Based on the latest simulations, Dimers' proven Liga MX model predicts Cruz Azul as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Cruz Azul vs. Santos Laguna predictions page.

Cruz Azul vs. Santos Laguna prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Saturday's Liga MX matchup between Cruz Azul and Santos Laguna 10,000 times as part of our Liga MX predictions coverage.

Our leading predictive model suggests a 79.3% chance of Cruz Azul winning, a 7.2% chance for Santos Laguna, and a 13.5% chance of a draw.

Cruz Azul vs. Santos Laguna odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Market	Cruz Azul	Santos Laguna	Draw
Moneyline	-475	+1300	+600

All odds are correct at the time of publication and are subject to change.

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Cruz Azul vs. Santos Laguna picks and best bets

Our model's biggest edge in today's Cruz Azul vs. Santos Laguna matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Cruz Azul vs. Santos Laguna: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 2-0 Cruz Azul win being the most probable:

Final Score	Probability
CAZ 2-0 SLA	12.4%
CAZ 3-0 SLA	11%
CAZ 1-0 SLA	9.3%

When it comes to the both teams to score (BTTS) market, we project a 46.3% chance that both teams scoring, and a 53.7% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations.

Cruz Azul vs. Santos Laguna game-day updates and essential details

Saturday's action between Cruz Azul and Santos Laguna at Estadio Olímpico Universitario is scheduled to commence at 9:00PM ET.

• Who: Cruz Azul vs. Santos Laguna
• Date: Saturday, August 16, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Estadio Olímpico Universitario

Dimers.com's full preview of Saturday's Cruz Azul vs. Santos Laguna matchup includes our prediction, picks and the latest betting odds.

Before making any Santos Laguna vs. Cruz Azul picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, Cruz Azul has a 79.3% win probability on Saturday, Santos Laguna has a 7.2% win probability, and there is a 13.5% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Cruz Azul vs. Santos Laguna insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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