Creighton vs. DePaul Prediction: Creighton Predicted to Win College Basketball Matchup [1/21/2025]

DePaul will take on the favored Creighton in college basketball action at Wintrust Arena on Tuesday, commencing at 9:00PM ET.

Based on updated simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Creighton as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Creighton-DePaul game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows Creighton with a win probability of 76%, compared to 24% for DePaul."

For further insights into Tuesday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Creighton vs. DePaul predictions page.

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Creighton vs. DePaul Game-Day Updates and Essential Details

Tuesday's college basketball matchup between DePaul and Creighton at Wintrust Arena is scheduled to commence at 9:00PM ET.

• Who: Creighton vs. DePaul
• Date: Tuesday, January 21, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Wintrust Arena
• Tickets: Get tickets for the game on Ticketmaster

Dimers.com's comprehensive preview of Tuesday's Creighton vs. DePaul matchup includes our prediction, picks and the latest betting odds.

Before making any Creighton vs. DePaul picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Creighton vs. DePaul Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and statistical analysis, we have simulated the result of Tuesday's NCAA basketball matchup between Creighton and DePaul 10,000 times as part of our college basketball predictions coverage.

Our leading predictive model currently gives Creighton a 76% chance of defeating DePaul. Our predicted final score has Creighton winning 76-68.

According to our model, DePaul (+7.5) has a 52% chance of covering the spread, while the over/under total of 144.5 points has a 52% chance of going over.

Creighton vs. DePaul Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Creighton	DePaul
Spread	-7.5 (-102)	+7.5 (-115)
Moneyline	-295	+240
Total	o144.5 (-105)	u144.5 (-110)

All odds are correct at the time of publication and are subject to change.

Creighton vs. DePaul Picks

Our model's strongest edge in today's Creighton vs. DePaul matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Conclusion

We predict Creighton, with a 76% win probability, will likely beat DePaul on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Creighton vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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