Rockies vs. Mariners prediction: Seattle favored to win Thursday's MLB matchup [9/25/2025]

MLB action continues on Thursday at 9:40PM ET as the Colorado Rockies take on the favored Seattle Mariners at T-Mobile Park.

The Mariners will send Emerson Hancock (4-5, 5.13 ERA) to the mound, while the Rockies have opted for Bradley Blalock (2-5, 9.16 ERA).

Based on the latest simulations, Dimers' proven MLB model predicts the Mariners as the most likely winner of today's game.

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Rockies vs. Mariners predictions page.

Mariners vs. Rockies prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Rockies and Mariners 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Mariners a 70% chance of defeating the Rockies.

According to our model, the Mariners (-1.5) have a 53% chance of covering the run line, while the 7.5-run over/under has a 63% chance of going over.

Rockies vs. Mariners odds [9/25/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Mariners
Run Line	+1.5 (+118)	-1.5 (-135)
Moneyline	+260	-300
Total	o7.5 (-120)	u7.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Mariners picks and best bets

Our model's strongest edge in today's Rockies vs. Mariners matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Rockies vs. Mariners game-day updates and essential details

Thursday's MLB game between the Mariners and Rockies at T-Mobile Park is scheduled to begin at 9:40PM ET.

• Who: Colorado Rockies vs. Seattle Mariners
• Date: Thursday, September 25, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: T-Mobile Park

Dimers' in-depth preview of Thursday's Rockies vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Rockies vs. Mariners picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mariners, with a 70% win probability, will likely beat the Rockies on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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