Rockies vs. Padres prediction: San Diego favored to win Sunday's MLB matchup [9/14/2025]

The San Diego Padres and Colorado Rockies will meet in MLB action at PETCO Park on Sunday, starting at 4:10PM ET.

Yu Darvish (3-5, 5.65 ERA) will start for the Padres, while the Rockies have opted for Germán Márquez (3-13, 6.31 ERA).

Based on the latest simulations, Dimers' advanced MLB model predicts the Padres as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Rockies-Padres game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Padres with a win probability of 72%, while the Rockies have 28%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Rockies vs. Padres predictions page.

Padres vs. Rockies prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Sunday's MLB matchup between the Rockies and Padres 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Padres a 72% chance of beating the Rockies.

According to our model, the Padres (-1.5) have a 53% chance of covering the run line, while the over/under total of 8 runs has a 52% chance of going over.

Rockies vs. Padres odds [9/14/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Padres
Run Line	+1.5 (+120)	-1.5 (-144)
Moneyline	+260	-310
Total	o8 (-114)	u8 (-101)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Padres picks and best bets

Our model's biggest edge in today's Rockies vs. Padres matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Rockies vs. Padres game-day updates and essential details

Sunday's MLB matchup between the Padres and Rockies at PETCO Park is scheduled to start at 4:10PM ET.

• Who: Colorado Rockies vs. San Diego Padres
• Date: Sunday, September 14, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: PETCO Park

Dimers' in-depth preview of Sunday's Rockies vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Rockies vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Padres, with a 72% win probability, will likely beat the Rockies on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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