Rockies vs. Padres prediction: San Diego favored to win Saturday's MLB matchup [9/13/2025]

The San Diego Padres will square off with the Colorado Rockies in MLB action at PETCO Park on Saturday, beginning at 8:40PM ET.

The Padres will start Dylan Cease (7-11, 4.71 ERA), while the Rockies are going with Bradley Blalock (1-4, 8.62 ERA).

Based on updated simulations, Dimers' advanced MLB model predicts the Padres as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Rockies vs. Padres predictions page.

Padres vs. Rockies prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB matchup between the Rockies and Padres 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Padres a 74% chance of beating the Rockies.

According to our model, the Padres (-1.5) have a 56% chance of covering the run line, while the over/under total of 8 runs has a 53% chance of going over.

Rockies vs. Padres odds [9/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Padres
Run Line	+1.5 (+132)	-1.5 (-156)
Moneyline	+300	-364
Total	o8 (-105)	u8 (-110)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Padres picks and best bets

Our model's biggest edge in today's Rockies vs. Padres matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Rockies vs. Padres game-day updates and essential details

Saturday's MLB matchup between the Padres and Rockies at PETCO Park is scheduled to begin at 8:40PM ET.

• Who: Colorado Rockies vs. San Diego Padres
• Date: Saturday, September 13, 2025
• Time: 8:40PM ET/5:40PM PT
• Venue: PETCO Park

Dimers' full preview of Saturday's Rockies vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Rockies vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Padres, with a 74% win probability, will likely beat the Rockies on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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