Rockies vs. Pirates prediction: Why Pittsburgh is favored to win Friday's MLB matchup [8/22/2025]

The Pittsburgh Pirates will take on the Colorado Rockies in MLB action at PNC Park on Friday, starting at 6:40PM ET.

Braxton Ashcraft (3-2, 3.02 ERA) will get the ball for the Pirates, while the Rockies have opted for Antonio Senzatela (4-14, 7.00 ERA).

Based on the latest simulations, Dimers' advanced MLB model predicts the Pirates as the most likely winner of today's game.

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Rockies vs. Pirates predictions page.

Pirates vs. Rockies prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Friday's MLB game between the Rockies and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Pirates a 62% chance of beating the Rockies.

According to our model, the Rockies (+1.5) have a 57% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Rockies vs. Pirates odds [8/22/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Pirates
Run Line	+1.5 (-110)	-1.5 (-108)
Moneyline	+192	-220
Total	o8.5 (-102)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Pirates picks and best bets

Our model's biggest edge in today's Rockies vs. Pirates matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Rockies vs. Pirates game-day updates and essential details

Friday's MLB matchup between the Pirates and Rockies at PNC Park is scheduled to commence at 6:40PM ET.

• Who: Colorado Rockies vs. Pittsburgh Pirates
• Date: Friday, August 22, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's full preview of Friday's Rockies vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Rockies vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 62% win probability, will likely beat the Rockies on Friday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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