Rockies vs. Astros prediction: Houston favored to win Wednesday's MLB matchup [8/27/2025]

The Houston Astros will face the Colorado Rockies in MLB action at Daikin Park on Wednesday, commencing at 8:10PM ET.

Framber Valdez (11-7, 3.32 ERA) will be on the bump for the Astros, up against Chase Dollander (2-10, 6.92 ERA) for the Rockies.

Based on updated simulation results, Dimers' advanced MLB model predicts the Astros as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Rockies-Astros game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Astros' chance of winning at 71%, with the Rockies at 29%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Rockies vs. Astros predictions page.

Astros vs. Rockies prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Wednesday's MLB game between the Rockies and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Astros a 71% chance of defeating the Rockies.

According to our model, the Astros (-1.5) have a 53% chance of covering the run line, while the over/under total of 8 runs has a 51% chance of going over.

Rockies vs. Astros odds [8/27/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Astros
Run Line	+1.5 (+114)	-1.5 (-132)
Moneyline	+250	-275
Total	o8 (-105)	u8 (-110)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Astros picks and best bets

Our model's strongest edge in today's Rockies vs. Astros matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Rockies vs. Astros game-day updates and essential details

Wednesday's MLB game between the Astros and Rockies at Daikin Park is scheduled to commence at 8:10PM ET.

• Who: Colorado Rockies vs. Houston Astros
• Date: Wednesday, August 27, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Wednesday's Rockies vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Rockies vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Astros, with a 71% win probability, will likely beat the Rockies on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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