Rockies vs. Diamondbacks Prediction: Arizona Predicted to Win Friday's MLB Matchup [5/16/2025]

The Arizona Diamondbacks will square off with the Colorado Rockies in MLB action at Chase Field on Friday, commencing at 9:40PM ET.

The Diamondbacks will send Corbin Burnes (2-1, 2.95 ERA) to the mound, while the Rockies have opted for Carson Palmquist (0-0, 0.00 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Colorado-Arizona game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Diamondbacks' chance of winning is 72%, while the Rockies' is 28%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Rockies vs. Diamondbacks predictions page.

Diamondbacks vs. Rockies Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the result of Friday's MLB game between the Rockies and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Diamondbacks a 72% chance of beating the Rockies.

According to our model, the Diamondbacks (-1.5) have a 55% chance of covering the run line, while the over/under total of 9 runs has a 54% chance of staying under.

Rockies vs. Diamondbacks Odds [5/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rockies	Diamondbacks
Run Line	+1.5 (+154)	-1.5 (-184)
Moneyline	+310	-375
Total	o9 (+100)	u9 (-114)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Diamondbacks Picks and Best Bets

Our model's biggest edge in today's Rockies vs. Diamondbacks matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Rockies vs. Diamondbacks Game-Day Updates and Essential Details

Friday's MLB game between the Diamondbacks and Rockies at Chase Field is scheduled to begin at 9:40PM ET.

• Who: Colorado Rockies vs. Arizona Diamondbacks
• Date: Friday, May 16, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: Chase Field

Dimers.com's comprehensive preview of Friday's Rockies vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Colorado vs. Arizona picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Diamondbacks, with a 72% win probability, will likely beat the Rockies on Friday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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