College Basketball Picks Today: Wednesday's Best Bets Include Two Spread Plays [2/26/2025]

College basketball betting is back for another attractive playoffs slate on 2/26, and we're here to share our top picks for Wednesday's NCAAM action.

Today's college basketball best bets come from a range of matchups, including SMU vs. California and San Francisco vs. Oregon State, with this article updated throughout the day to highlight the most attractive upcoming games.

Featuring a standout spread play at 11:00PM ET, these picks are based on advanced simulations and machine learning.

For unlimited access to everything Dimers has to offer on Wednesday, February 26, 2025—including our complete set of college basketball picks and best bets—check out Dimers Pro.

Sign up with code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Perfect timing for the playoffs.

List of College Basketball Picks Tonight [2/26, Updated: 10:31PM ET]

After digging deep into the numbers and conducting thousands of simulations, our independent predictive analytics model has identified the best college basketball bets for Wednesday, February 26, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro subscribers.

California +3.5 (-104)

• Edge: 4.8%
• Probability: 55.8%
• Matchup: SMU vs. California (11:00PM ET, Wednesday)

Our model has pinpointed the next college basketball betting opportunity tonight, which comes in the SMU vs. California game. We recommend a spread bet on California +3.5 at -104 odds, offering an edge of 4.8%.

Oregon State -3.5 (-108)

• Edge: 3.9%
• Probability: 55.8%
• Matchup: San Francisco vs. Oregon State (11:00PM ET, Wednesday)

Our model has found another great college basketball bet for Wednesday's NCAA action, this time in the game between San Francisco and Oregon State. We suggest placing a spread wager on Oregon State -3.5 at -108 odds, with our analysis showing a compelling 3.9% edge.

MORE: College Basketball Props

Oregon State ML (-166)

• Edge: 3.6%
• Probability: 66%
• Matchup: San Francisco vs. Oregon State (11:00PM ET, Wednesday)

Our next pick for Wednesday's college basketball action is also from the San Francisco vs. Oregon State game. We recommend a bet on Oregon State ML at -166 odds. Our model suggests a favorable 3.6% edge for this wager.

MORE: Wednesday Parlay Picker

NCAAM Best Bets: Wednesday, 2/26/2025

As of 10:31PM ET, here are the next three college basketball bets recommended by our model:

Matchup	Bet	Odds	Edge
SMU vs. California	California +3.5	-104 @ FanDuel	4.8%
San Francisco vs. Oregon State	Oregon State -3.5	-108 @ DraftKings	3.9%
San Francisco vs. Oregon State	Oregon State ML	-166 @ FanDuel	3.6%

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Wednesday's full suite of NCAAM picks is highlighted by a spread opportunity with a substantial 5.7% edge over the sportsbook odds.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for February 26, 2025.

List of Upcoming College Basketball Games To Bet On

• San Francisco vs. Oregon State (11:00PM ET, Wednesday)
• SMU vs. California (11:00PM ET, Wednesday)
• Albany vs. UMBC (6:00PM ET, Thursday)
• Samford vs. Virginia Military (6:00PM ET, Thursday)
• Bryant University vs. Massachusetts-Lowell (6:00PM ET, Thursday)
• North Texas vs. Florida Atlantic (7:00PM ET, Thursday)
• William & Mary vs. Towson (7:00PM ET, Thursday)
• Hofstra vs. Stony Brook (7:00PM ET, Thursday)
• Chattanooga vs. UNC Greensboro (7:00PM ET, Thursday)
• Northern Kentucky vs. Purdue Fort Wayne (7:00PM ET, Thursday)

More About CBB

This article is part of our college basketball player props and college basketball best bets series.

For more NCAAB betting content, we have college basketball betting news and the latest March Madness odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.