College Basketball Picks Today: Tuesday's Best Bets Include Gonzaga vs. Santa Clara Play [2/25/2025]

College basketball betting is back for another attractive playoffs day on 2/25, and we're here to give you our top picks for Tuesday's NCAAM action.

Today's college basketball best bets come from a range of matchups, including the Gonzaga vs. Santa Clara game at 11:00PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Led by a standout spread play with an edge of 9.3%, these picks are based on extensive simulations and machine learning.

For unlimited access to everything Dimers has to offer on Tuesday, February 25, 2025—including our complete suite of college basketball picks and best bets—check out Dimers Pro.

Sign up with code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Perfect timing for the playoffs.

List of College Basketball Picks Tonight [2/25, Updated: 10:31PM ET]

After crunching the numbers and running thousands of simulations, our famous predictive analytics model has identified the best college basketball bets for Tuesday, February 25, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro users.

Santa Clara +6.5 (-105)

• Edge: 9.3%
• Probability: 60.5%
• Matchup: Gonzaga vs. Santa Clara (11:00PM ET, Tuesday)

Our model has pinpointed the next college basketball betting opportunity tonight, which comes in the Gonzaga vs. Santa Clara matchup. We recommend a spread bet on Santa Clara +6.5 at -105 odds, offering an edge of 9.3%.

Santa Clara ML (+240)

• Edge: 6.3%
• Probability: 35.7%
• Matchup: Gonzaga vs. Santa Clara (11:00PM ET, Tuesday)

Our model has found another great college basketball bet for Tuesday's NCAA action, again in the game between Gonzaga and Santa Clara. We suggest placing a wager on Santa Clara ML at +240 odds, with our analysis showing a compelling 6.3% edge.

MORE: College Basketball Props

Gonzaga vs. Santa Clara Under 163.5 Points (-110)

• Edge: 2.5%
• Probability: 54.9%
• Matchup: Gonzaga vs. Santa Clara (11:00PM ET, Tuesday)

Our next pick for tonight's college basketball action is also from the Gonzaga vs. Santa Clara matchup. We recommend an over/under bet on Under 163.5 Points at -110 odds. Our model indicates a favorable 2.5% edge for this wager.

MORE: Tuesday Parlay Picker

NCAAM Best Bets: Tuesday, 2/25/2025

As of 10:31PM ET, here are the next three college basketball bets recommended by our model:

Matchup	Bet	Odds	Edge
Gonzaga vs. Santa Clara	Santa Clara +6.5	-105 @ FanDuel	9.3%
Gonzaga vs. Santa Clara	Santa Clara ML	+240 @ DraftKings	6.3%
Gonzaga vs. Santa Clara	Under 163.5 Points	-110 @ FanDuel	2.5%

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you instant access to today's best bets across all sports, powered by our advanced model.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for February 25, 2025.

List of Upcoming College Basketball Games To Bet On

• New Mexico vs. San Diego State (11:00PM ET, Tuesday)
• Gonzaga vs. Santa Clara (11:00PM ET, Tuesday)
• Boston University vs. Lehigh (6:00PM ET, Wednesday)
• Mercer vs. East Tennessee State (6:00PM ET, Wednesday)
• Michigan State vs. Maryland (6:30PM ET, Wednesday)
• Georgetown vs. Connecticut (6:30PM ET, Wednesday)
• Duquesne vs. La Salle (6:30PM ET, Wednesday)
• Ole Miss vs. Auburn (7:00PM ET, Wednesday)
• Notre Dame vs. Clemson (7:00PM ET, Wednesday)
• Vanderbilt vs. Texas A&M (7:00PM ET, Wednesday)

More About CBB

This article is part of our college basketball player props and college basketball best bets series.

For more NCAAB betting content, we have college basketball betting news and the latest March Madness odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.