Coastal Carolina vs. South Alabama prediction: South Alabama favored to win in college football Week 4, 2025

South Alabama will square off with Coastal Carolina in Week 4 college football action at Hancock Whitney Stadium on Saturday, starting at 7:00PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts South Alabama as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Coastal Carolina vs. South Alabama predictions page.

Coastal Carolina vs. South Alabama prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of Coastal Carolina vs. South Alabama 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives South Alabama an 82% chance of defeating Coastal Carolina. Our predicted final score has South Alabama winning 32-18.

According to our model, Coastal Carolina (+14.5) has a 53% chance of covering the spread, while the over/under total of 51.5 points has a 53% chance of going over.

Coastal Carolina vs. South Alabama odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Coastal Carolina	South Alabama
Spread	+14.5 (-110)	-14.5 (-108)
Moneyline	+500	-630
Total	o51.5 (-105)	u51.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Coastal Carolina vs. South Alabama picks and best bets

Our model's strongest edge in today's Coastal Carolina vs. South Alabama matchup is on the spread.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Coastal Carolina vs. South Alabama game-day updates and essential details

Saturday's college football matchup between South Alabama and Coastal Carolina at Hancock Whitney Stadium is scheduled to begin at 7:00PM ET.

• Who: Coastal Carolina vs. South Alabama
• Date: Saturday, September 20, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Hancock Whitney Stadium

Dimers' full preview of Saturday's Coastal Carolina vs. South Alabama matchup includes our prediction, picks and the latest betting odds.

Before making any Coastal Carolina vs. South Alabama picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict South Alabama, with an 82% win probability, will likely beat Coastal Carolina on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Coastal Carolina vs. South Alabama insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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