Guardians vs. Rays prediction: Why Tampa Bay is favored to win Sunday's MLB matchup [9/7/2025]

The Tampa Bay Rays and Cleveland Guardians will meet in MLB action at George M. Steinbrenner Field on Sunday, starting at 12:10PM ET.

Drew Rasmussen (10-5, 2.74 ERA) will get the ball for the Rays, up against Parker Messick (1-0, 2.08 ERA) for the Guardians.

Based on the latest simulations, Dimers' proven MLB model predicts the Rays as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Guardians-Rays game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Rays with a win probability of 59%, while the Guardians have 41%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Guardians vs. Rays predictions page.

Rays vs. Guardians prediction: Who will win, cover the run line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB game between the Guardians and Rays 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Rays a 59% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 60% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of staying under.

Guardians vs. Rays odds [9/7/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Guardians	Rays
Run Line	+1.5 (-155)	-1.5 (+134)
Moneyline	+138	-160
Total	o8.5 (-102)	u8.5 (-118)

All odds are correct at the time of publication and are subject to change.

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Guardians vs. Rays picks and best bets

Our model's biggest edge in today's Guardians vs. Rays matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Guardians vs. Rays game-day updates and essential details

Sunday's MLB game between the Rays and Guardians at George M. Steinbrenner Field is scheduled to begin at 12:10PM ET.

• Who: Cleveland Guardians vs. Tampa Bay Rays
• Date: Sunday, September 7, 2025
• Time: 12:10PM ET/9:10AM PT
• Venue: George M. Steinbrenner Field

Dimers.com's full preview of Sunday's Guardians vs. Rays matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. Rays picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Rays, with a 59% win probability, will likely beat the Guardians on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Rays insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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