Guardians vs. Yankees Prediction: Yankees Predicted to Win Tuesday's MLB Matchup [6/3/2025]

The New York Yankees will face the Cleveland Guardians in MLB action at Yankee Stadium on Tuesday, starting at 7:05PM ET.

The Yankees will start Carlos Rodón (7-3, 2.60 ERA), pitting him against Tanner Bibee (4-5, 3.86 ERA) for the Guardians.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Yankees as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Cleveland-NY Yankees game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Yankees with a win probability of 64%, compared to 36% for the Guardians."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Guardians vs. Yankees predictions page.

Yankees vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB matchup between the Guardians and Yankees 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Yankees a 64% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 54% chance of covering the run line, while the 8-run over/under has a 51% chance of staying under.

Guardians vs. Yankees Odds [6/3/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Guardians	Yankees
Run Line	+1.5 (-120)	-1.5 (+104)
Moneyline	+168	-200
Total	o8 (-102)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Guardians vs. Yankees Picks and Best Bets

Our model's biggest edge in today's Guardians vs. Yankees matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Guardians vs. Yankees Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Yankees and Guardians at Yankee Stadium is scheduled to start at 7:05PM ET.

• Who: Cleveland Guardians vs. New York Yankees
• Date: Tuesday, June 3, 2025
• Time: 7:05PM ET/4:05PM PT
• Venue: Yankee Stadium

Dimers.com's comprehensive preview of Tuesday's Guardians vs. Yankees matchup includes our prediction, picks and the latest betting odds.

Before making any Cleveland vs. NY Yankees picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Yankees, with a 64% win probability, will likely beat the Guardians on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.