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Guardians vs. Astros Prediction: Houston Predicted to Win Tuesday's MLB Matchup [7/8/2025]
Our expert prediction for Tuesday's Cleveland Guardians vs Houston Astros matchup.

The Houston Astros and Cleveland Guardians will lock horns in MLB action at Daikin Park on Tuesday, starting at 8:10PM ET.
Hunter Brown (9-3, 1.82 ERA) will be on the bump for the Astros, while the Guardians will counter with Joey Cantillo (1-0, 3.41 ERA).
Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.
For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Guardians vs. Astros predictions page.
Astros vs. Guardians Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Tuesday's MLB matchup between the Guardians and Astros 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Astros a 64% chance of beating the Guardians.
According to our model, the Guardians (+1.5) have a 55% chance of covering the run line, while the over/under total of 7 runs has a 51% chance of going over.
Guardians vs. Astros Odds [7/8/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Guardians | Astros |
---|---|---|
Run Line | +1.5 (-123) | -1.5 (+105) |
Moneyline | +176 | -200 |
Total | o7 (-110) | u7 (-102) |
All odds are correct at the time of publication and are subject to change.
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Guardians vs. Astros Picks and Best Bets
Our model's strongest edge in today's Guardians vs. Astros matchup is on the over/under.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the predictions featured below.
Guardians vs. Astros Game-Day Updates and Essential Details
Tuesday's MLB action between the Astros and Guardians at Daikin Park is scheduled to commence at 8:10PM ET.
- Who: Cleveland Guardians vs. Houston Astros
- Date: Tuesday, July 8, 2025
- Time: 8:10PM ET/5:10PM PT
- Venue: Daikin Park
Dimers.com's comprehensive preview of Tuesday's Guardians vs. Astros matchup includes our prediction, picks and the latest betting odds.
Before making any Guardians vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Astros, with a 64% win probability, will likely beat the Guardians on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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