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Guardians vs. Tigers Prediction: Detroit Predicted to Win Sunday's MLB Matchup [5/25/2025]

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Written by Jason Bevilacqua

Our expert prediction for Sunday's Cleveland Guardians vs Detroit Tigers matchup.

Cleveland Guardians-Detroit Tigers Predictions and Game Preview.
Comerica Park sets the stage for the MLB matchup between the Cleveland Guardians and Detroit Tigers this Sunday.

The Detroit Tigers will square off with the Cleveland Guardians in MLB action at Comerica Park on Sunday, commencing at 11:35AM ET.

Tarik Skubal (4-2, 2.87 ERA) will start on the mound for the Tigers, up against Logan Allen (2-2, 3.86 ERA) for the Guardians.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Tigers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Cleveland-Detroit game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Tigers with a win probability of 70%, while the Guardians have 30%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Guardians vs. Tigers predictions page.

Tigers vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Sunday's MLB game between the Guardians and Tigers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Tigers a 70% chance of defeating the Guardians.

According to our model, the Tigers (-1.5) have a 51% chance of covering the run line, while the over/under total of 7 runs has an equal 50-50 chance of hitting.

 

Guardians vs. Tigers Odds [5/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Guardians Tigers
Run Line +1.5 (+114) -1.5 (-134)
Moneyline +260 -300
Total o7 (+100) u7 (-120)

All odds are correct at the time of publication and are subject to change.

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Guardians vs. Tigers Picks and Best Bets

Our model's biggest edge in today's Guardians vs. Tigers matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Guardians vs. Tigers Game-Day Updates and Essential Details

Sunday's MLB game between the Tigers and Guardians at Comerica Park is scheduled to start at 11:35AM ET.

Dimers.com's in-depth preview of Sunday's Guardians vs. Tigers matchup includes our prediction, picks and the latest betting odds.

Before making any Cleveland vs. Detroit picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Tigers, with a 70% win probability, will likely beat the Guardians on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Tigers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate probabilities for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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