Guardians vs. White Sox Prediction: Cleveland Predicted to Win Sunday's MLB Matchup [7/13/2025]

The Chicago White Sox will square off with the Cleveland Guardians in MLB action at Rate Field on Sunday, starting at 2:10PM ET.

The White Sox will have Aaron Civale (1-6, 5.17 ERA) as their starting pitcher, up against Joey Cantillo (1-0, 3.78 ERA) for the Guardians.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Guardians as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Guardians-White Sox game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Guardians with a win probability of 57%, while the White Sox have 43%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Guardians vs. White Sox predictions page.

White Sox vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Sunday's MLB game between the Guardians and White Sox 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Guardians a 57% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 57% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of staying under.

Guardians vs. White Sox Odds [7/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Guardians	White Sox
Run Line	-1.5 (+125)	+1.5 (-140)
Moneyline	-135	+120
Total	o8.5 (-115)	u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Guardians vs. White Sox Picks and Best Bets

Our model's strongest edge in today's Guardians vs. White Sox matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Guardians vs. White Sox Game-Day Updates and Essential Details

Sunday's MLB action between the White Sox and Guardians at Rate Field is scheduled to commence at 2:10PM ET.

• Who: Cleveland Guardians vs. Chicago White Sox
• Date: Sunday, July 13, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Rate Field

Dimers.com's in-depth preview of Sunday's Guardians vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Guardians, with a 57% win probability, will likely beat the White Sox on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most up-to-date projections for the World Series, American League, National League and each division.