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Guardians vs. White Sox Prediction: Cleveland Predicted to Win Saturday's MLB Matchup [7/12/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Saturday's Cleveland Guardians vs Chicago White Sox matchup.
The Chicago White Sox will take on the Cleveland Guardians in MLB action at Rate Field on Saturday, beginning at 4:10PM ET.
The White Sox will have Sean Burke (4-8, 4.40 ERA) as their starting pitcher, while the Guardians have opted for Tanner Bibee (4-9, 4.36 ERA).
Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Guardians as the most likely winner of today's game.
For further insights into Saturday's matchup, including best bets and picks, visit our interactive Guardians vs. White Sox predictions page.
White Sox vs. Guardians Prediction: Who Will Win, Cover the Run Line?
Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB game between the Guardians and White Sox 10,000 times as part of our MLB predictions coverage.
Our independent predictive model gives the Guardians a 54% chance of beating the White Sox.
According to our model, the White Sox (+1.5) have a 59% chance of covering the run line, while the over/under total of 9.5 runs has a 60% chance of staying under.
Guardians vs. White Sox Odds [7/12/2025]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Guardians | White Sox |
|---|---|---|
| Run Line | -1.5 (+142) | +1.5 (-150) |
| Moneyline | -113 | +118 |
| Total | o9.5 (-122) | u9.5 (-107) |
All odds are correct at the time of publication and are subject to change.
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Guardians vs. White Sox Picks and Best Bets
Our model's strongest edge in today's Guardians vs. White Sox matchup is on the run line.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.
Guardians vs. White Sox Game-Day Updates and Essential Details
Saturday's MLB game between the White Sox and Guardians at Rate Field is scheduled to begin at 4:10PM ET.
- Who: Cleveland Guardians vs. Chicago White Sox
- Date: Saturday, July 12, 2025
- Time: 4:10PM ET/1:10PM PT
- Venue: Rate Field
Dimers.com's full preview of Saturday's Guardians vs. White Sox matchup includes our prediction, picks and the latest betting odds.
Before making any Guardians vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Guardians, with a 54% win probability, will likely beat the White Sox on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Guardians vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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