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Guardians vs. White Sox Prediction: Cleveland Predicted to Win Friday's MLB Matchup [7/11/2025]
Our expert prediction for Friday's Cleveland Guardians vs Chicago White Sox matchup.

The Chicago White Sox will take on the Cleveland Guardians, in what is expected to be a tight MLB game, at Rate Field on Friday, beginning at 8:10PM ET.
The White Sox will send Shane Smith (3-7, 4.20 ERA) to the mound, pitting him against Gavin Williams (5-4, 3.61 ERA) for the Guardians.
Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Guardians as the most likely winner of today's game.
For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Guardians vs. White Sox predictions page.
White Sox vs. Guardians Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and data analysis, we have simulated the result of Friday's MLB game between the Guardians and White Sox 10,000 times as part of our MLB predictions coverage.
Our independent predictive model currently gives the Guardians a 54% chance of defeating the White Sox.
According to our model, the White Sox (+1.5) have a 60% chance of covering the run line, while the over/under total of 8 runs has an equal 50-50 chance of hitting.
Guardians vs. White Sox Odds [7/11/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Guardians | White Sox |
---|---|---|
Run Line | -1.5 (+130) | +1.5 (-140) |
Moneyline | -132 | +118 |
Total | o8 (-115) | u8 (+100) |
All odds are correct at the time of publication and are subject to change.
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Guardians vs. White Sox Picks and Best Bets
Our model's strongest edge in today's Guardians vs. White Sox matchup is on the total.
Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free ⚾️ Picks
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Guardians vs. White Sox Game-Day Updates and Essential Details
Friday's MLB matchup between the White Sox and Guardians at Rate Field is scheduled to begin at 8:10PM ET.
- Who: Cleveland Guardians vs. Chicago White Sox
- Date: Friday, July 11, 2025
- Time: 8:10PM ET/5:10PM PT
- Venue: Rate Field
Dimers.com's full preview of Friday's Guardians vs. White Sox matchup includes our prediction, picks and the latest betting odds.
Before making any Guardians vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Guardians, with a 54% win probability, will likely beat the White Sox on Friday.
AI and automation have enhanced this article to quickly deliver accurate Guardians vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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