Guardians vs. Cubs Prediction: Cubs Predicted to Win Tuesday's MLB Matchup [7/1/2025]

The Chicago Cubs and Cleveland Guardians are scheduled to meet in MLB action at Wrigley Field on Tuesday, starting at 8:05PM ET.

Matthew Boyd (7-3, 2.65 ERA) will start on the mound for the Cubs, while the Guardians will counter with Gavin Williams (5-3, 3.68 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Guardians-Cubs game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Cubs with a win probability of 65%, compared to 35% for the Guardians."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Guardians vs. Cubs predictions page.

Cubs vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB matchup between the Guardians and Cubs 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Cubs a 65% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 54% chance of covering the run line, while the 8.5-run over/under has a 52% chance of staying under.

Guardians vs. Cubs Odds [7/1/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Guardians	Cubs
Run Line	+1.5 (-120)	-1.5 (+105)
Moneyline	+170	-200
Total	o8.5 (-106)	u8.5 (-112)

All odds are correct at the time of publication and are subject to change.

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Guardians vs. Cubs Picks and Best Bets

Our model's biggest edge in today's Guardians vs. Cubs matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Guardians vs. Cubs Game-Day Updates and Essential Details

Tuesday's MLB action between the Cubs and Guardians at Wrigley Field is scheduled to commence at 8:05PM ET.

• Who: Cleveland Guardians vs. Chicago Cubs
• Date: Tuesday, July 1, 2025
• Time: 8:05PM ET/5:05PM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Tuesday's Guardians vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cubs, with a 65% win probability, will likely beat the Guardians on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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