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Guardians vs. Orioles Prediction: Baltimore Predicted to Win Tuesday's MLB Matchup [4/15/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Tuesday's Cleveland Guardians vs Baltimore Orioles matchup.
The Baltimore Orioles and Cleveland Guardians will meet in MLB action at Oriole Park at Camden Yards on Tuesday, starting at 7:05PM ET.
Charlie Morton (0-3, 8.78 ERA) will be on the bump for the Orioles, while the Guardians have opted for Logan Allen (0-1, 3.60 ERA).
Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Orioles as the most likely winner of today's game.
"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Cleveland-Baltimore game," said Dimers' Chief Content Officer, Nick Slade.
"By incorporating recent updates and various factors, our prediction shows the Orioles with a win probability of 58%, compared to 42% for the Guardians."
For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Guardians vs. Orioles predictions page.
Guardians vs. Guardians Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Tuesday's MLB game between the Guardians and Orioles 10,000 times as part of our MLB predictions coverage.
Our famous predictive model currently gives the Orioles a 58% chance of beating the Guardians.
According to our model, the Guardians (+1.5) have a 61% chance of covering the run line, while the 9-run over/under has a 52% chance of staying under.
Guardians vs. Orioles Odds [4/15/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Guardians | Orioles |
|---|---|---|
| Run Line | +1.5 (-162) | -1.5 (+146) |
| Moneyline | +130 | -150 |
| Total | o9 (+100) | u9 (-118) |
All odds are correct at the time of publication and are subject to change.
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Guardians vs. Orioles Picks and Best Bets
Our model's biggest edge in today's Guardians vs. Orioles matchup is on the over/under.
Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free ⚾️ Picks
Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.
Guardians vs. Orioles Game-Day Updates and Essential Details
Tuesday's MLB action between the Orioles and Guardians at Oriole Park at Camden Yards is scheduled to begin at 7:05PM ET.
- Who: Cleveland Guardians vs. Baltimore Orioles
- Date: Tuesday, April 15, 2025
- Time: 7:05PM ET/4:05PM PT
- Venue: Oriole Park at Camden Yards
Dimers.com's full preview of Tuesday's Guardians vs. Orioles matchup includes our prediction, picks and the latest betting odds.
Before making any Cleveland vs. Baltimore picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Orioles, with a 58% win probability, will likely beat the Guardians on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on MLB
Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most accurate predictions for the World Series, American League, National League and each division.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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