Cleveland Browns vs. Detroit Lions updated prediction featuring Quinshon Judkins, Jahmyr Gibbs [Week 4, 2025]

Dimers' latest NFL predictions are live for Detroit Lions and Cleveland Browns in Week 4, with our model giving the Lions a 80% of winning against the Browns on Sunday.

This update builds on our early Lions-Browns predictions, providing renewed win probabilities, score projections, and TD predictions for Quinshon Judkins, Jahmyr Gibbs, and more.

For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Browns vs. Lions page.

What's changed? Cleveland vs. Detroit updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Browns vs. Lions matchup stacks up. Here are the updated forecasted:

• Straight Up Win Probabilities: Browns 20%, Lions 80%
• Predicted Final Score: Browns 17-26 Lions
• Spread: Browns (+9.5) 53%, Lions (-9.5) 47%
• Total Points (44.5): Over 50%, Under 50%

As of September 25, 2025, these Browns-Lions numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New projections highlight the top candidates to find the end zone in Browns-Lions on Sunday:

Cleveland Browns

• Quinshon Judkins: 41.7% probability
• Jerry Jeudy: 24.7% probability
• Cedric Tillman: 23.7% probability

Detroit Lions

• Jahmyr Gibbs: 59.5% probability
• David Montgomery: 49.4% probability
• Amon-Ra St. Brown: 42.9% probability

Browns vs. Lions latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Browns +9.5 (-110), Lions -9.5 (-110)
• Moneyline: Browns +400, Lions -520
• Total: Over/Under 44.5 (-105/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Browns vs. Lions Week 4 details

The NFL Week 4 matchup between the Lions and Browns at Ford Field is scheduled for September 28, 2025.

• Who: Cleveland Browns vs. Detroit Lions
• Date: Sunday, September 28, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Ford Field

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Conclusion

We predict the Lions, with an 80% win probability, will likely beat the Browns in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Browns vs. Lions matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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