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Clemson vs. Louisville Prediction: Louisville Predicted to Win College Basketball Matchup [1/7/2025]

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Written by Dave Garofolo

Our expert prediction for Tuesday's Clemson vs Louisville matchup.

Clemson-Louisville Predictions and Game Preview.
KFC Yum! Center sets the stage for the college basketball matchup between Clemson and Louisville this Tuesday.

Louisville will face Clemson in college basketball action at KFC Yum! Center on Tuesday, commencing at 7:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Louisville as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Clemson-Louisville game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows Louisville with a win probability of 59%, compared to 41% for Clemson."

For further insights into Tuesday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Clemson vs. Louisville predictions page.

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Clemson vs. Louisville Game-Day Updates and Essential Details

Tuesday's college basketball game between Louisville and Clemson at KFC Yum! Center is scheduled to start at 7:00PM ET.

Dimers.com's in-depth preview of Tuesday's Clemson vs. Louisville matchup includes our prediction, picks and the latest betting odds.

Before making any Clemson vs. Louisville picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Clemson vs. Louisville Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Clemson and Louisville 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model currently gives Louisville a 59% chance of defeating Clemson. Our predicted final score has Louisville winning 77-75.

According to our model, Clemson (+3.5) has a 56% chance of covering the spread, while the 147-point over/under has a 58% chance of going over.

 

Clemson vs. Louisville Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Clemson Louisville
Spread +3.5 (-110) -3.5 (-105)
Moneyline +135 -155
Total o147 (-108) u147 (-112)

All odds are correct at the time of publication and are subject to change.

Clemson vs. Louisville Picks

Our model's biggest edge in today's Clemson vs. Louisville matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Conclusion

We predict Louisville, with a 59% win probability, will likely beat Clemson on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Clemson vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on College Basketball

Keep up with the latest college basketball news, college basketball best bets and CBB parlay picks throughout the season. Plus, our March Madness odds provide the latest projections for every March Madness contender.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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