Cincinnati vs. Kansas prediction: Kansas favored to win in college football Week 5, 2025

Kansas and Cincinnati will meet in Week 5 college football action at David Booth Kansas Memorial Stadium on Saturday, starting at 12:00PM ET.

Based on updated simulations, Dimers' proven college football model predicts Kansas as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Cincinnati vs. Kansas predictions page.

Cincinnati vs. Kansas prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Cincinnati vs. Kansas 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Kansas a 67% chance of defeating Cincinnati. Our predicted final score has Kansas winning 29-23.

According to our model, Cincinnati (+13.5) has a 57% chance of covering the spread, while the 56.5-point over/under has a 58% chance of going over.

Cincinnati vs. Kansas odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Cincinnati	Kansas
Spread	+13.5 (-118)	-13.5 (-112)
Moneyline	+360	-210
Total	o56.5 (-110)	u56.5 (-118)

All odds are correct at the time of publication and are subject to change.

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Cincinnati vs. Kansas picks and best bets

Our model's strongest edge in today's Cincinnati vs. Kansas matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Cincinnati vs. Kansas game-day updates and essential details

Saturday's college football game between Kansas and Cincinnati at David Booth Kansas Memorial Stadium is scheduled to begin at 12:00PM ET.

• Who: Cincinnati vs. Kansas
• Date: Saturday, September 27, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: David Booth Kansas Memorial Stadium

Dimers' full preview of Saturday's Cincinnati vs. Kansas matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Kansas picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict Kansas, with a 67% win probability, will likely beat Cincinnati on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Cincinnati vs. Kansas insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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