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Reds vs. Nationals Prediction: Cincinnati Predicted to Win Wednesday's MLB Matchup [7/23/2025]

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Written by Dave Garofolo

Our expert prediction for Wednesday's Cincinnati Reds vs Washington Nationals matchup.

Cincinnati Reds-Washington Nationals Predictions and Game Preview.
Nationals Park sets the stage for the MLB matchup between the Cincinnati Reds and Washington Nationals this Wednesday.

The Washington Nationals will take on the Cincinnati Reds in MLB action at Nationals Park on Wednesday, commencing at 12:05PM ET.

Michael Soroka (3-7, 5.10 ERA) will start for the Nationals, while the Reds will counter with Nick Lodolo (7-6, 3.33 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Reds-Nationals game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Reds' chance of winning at 52%, with the Nationals at 48%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Reds vs. Nationals predictions page.

Nationals vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Reds and Nationals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Reds a 52% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 61% chance of covering the run line, while the over/under total of 8.5 runs has a 52% chance of staying under.

 

Reds vs. Nationals Odds [7/23/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Reds Nationals
Run Line -1.5 (+125) +1.5 (-146)
Moneyline -130 +110
Total o8.5 (-107) u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Reds vs. Nationals Picks and Best Bets

Our model's biggest edge in today's Reds vs. Nationals matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Reds vs. Nationals Game-Day Updates and Essential Details

Wednesday's MLB action between the Nationals and Reds at Nationals Park is scheduled to begin at 12:05PM ET.

Dimers.com's in-depth preview of Wednesday's Reds vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Nationals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 52% win probability, will likely beat the Nationals on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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