Reds vs. Pirates Prediction: Cincinnati Predicted to Win Tuesday's MLB Matchup [5/20/2025]

The Pittsburgh Pirates will take on the Cincinnati Reds in MLB action at PNC Park on Tuesday, commencing at 6:40PM ET.

Bailey Falter (2-3, 4.02 ERA) will start for the Pirates, up against Nick Martinez (2-4, 3.66 ERA) for the Reds.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Cincinnati-Pittsburgh game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Reds with a win probability of 55%, compared to 45% for the Pirates."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Reds vs. Pirates predictions page.

Pirates vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the result of Tuesday's MLB game between the Reds and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Reds a 55% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 60% chance of covering the run line, while the over/under total of 8 runs has a 53% chance of staying under.

Reds vs. Pirates Odds [5/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Pirates
Run Line	-1.5 (+125)	+1.5 (-137)
Moneyline	-142	+126
Total	o8 (-102)	u8 (-118)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Reds vs. Pirates matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Reds vs. Pirates Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Pirates and Reds at PNC Park is scheduled to start at 6:40PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Tuesday, May 20, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Tuesday's Reds vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Reds, with a 55% win probability, will likely beat the Pirates on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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