Reds vs. Pirates Prediction: Pittsburgh Predicted to Win Thursday's MLB Matchup [8/7/2025]

The Pittsburgh Pirates will square off with the Cincinnati Reds in MLB action at PNC Park on Thursday, starting at 6:40PM ET.

Paul Skenes (6-8, 2.02 ERA) will start for the Pirates, while the Reds are going with Brady Singer (9-8, 4.36 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Reds vs. Pirates predictions page.

Pirates vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Thursday's MLB game between the Reds and Pirates 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Pirates a 60% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 60% chance of covering the run line, while the over/under total of 7 runs has a 51% chance of staying under.

Reds vs. Pirates Odds [8/7/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Pirates
Run Line	+1.5 (-155)	-1.5 (+134)
Moneyline	+142	-165
Total	o7 (+100)	u7 (-121)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Reds vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Reds vs. Pirates matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Reds vs. Pirates Game-Day Updates and Essential Details

Thursday's MLB action between the Pirates and Reds at PNC Park is scheduled to commence at 6:40PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Thursday, August 7, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Thursday's Reds vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Sports Betting Deal Available for Kansas Today

To make the most of Thursday's exciting day of sports, headlined by the opening round at St. Jude Championship and continued NFL pre-season action, check out details on the latest Bet365 bonus in the state of Kansas that grants you $150 in bonus bets from a $5 bet. Don't miss out!

Conclusion

We predict the Pirates, with a 60% win probability, will likely beat the Reds on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.