Reds vs. Pirates Prediction: Cincinnati Predicted to Win Friday's MLB Matchup [8/8/2025]

The Pittsburgh Pirates and Cincinnati Reds are scheduled to meet in MLB action at PNC Park on Friday, starting at 6:40PM ET.

Mitch Keller (5-10, 3.89 ERA) will start for the Pirates, while the Reds will counter with Chase Burns (0-3, 6.04 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Reds vs. Pirates predictions page.

Pirates vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Reds and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Reds a 52% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 61% chance of covering the run line, while the 7.5-run over/under has a 52% chance of staying under.

Reds vs. Pirates Odds [8/8/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Pirates
Run Line	-1.5 (+140)	+1.5 (-170)
Moneyline	-124	+110
Total	o7.5 (+100)	u7.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Pirates Picks and Best Bets

Our model's biggest edge in today's Reds vs. Pirates matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Reds vs. Pirates Game-Day Updates and Essential Details

Friday's MLB game between the Pirates and Reds at PNC Park is scheduled to begin at 6:40PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Friday, August 8, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's full preview of Friday's Reds vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 52% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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