Reds vs. Brewers prediction: Cy Young candidate Freddy Peralta takes on Cincinnati today [9/28/2025]

MLB action continues on Sunday at 3:10PM ET as the Cincinnati Reds take on the Milwaukee Brewers at American Family Field.

The Brewers will start Cy Young fancy Freddy Peralta (17-6, 2.68 ERA), up against Brady Singer (14-11, 3.95 ERA) for the Reds.

Based on updated simulation results, Dimers' advanced MLB model projects the Brewers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Reds-Brewers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Brewers with a win probability of 57%, while the Reds have 43%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Reds vs. Brewers predictions page.

Brewers vs. Reds prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Sunday's MLB game between the Reds and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Brewers a 57% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 62% chance of covering the run line, while the 7.5-run over/under has a 60% chance of going over.

Reds vs. Brewers odds [9/28/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Brewers
Run Line	+1.5 (-175)	-1.5 (+158)
Moneyline	+115	-130
Total	o7.5 (-109)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Brewers picks and best bets

Our model's biggest edge in today's Reds vs. Brewers matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

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Reds vs. Brewers game-day updates and essential details

Sunday's MLB matchup between the Brewers and Reds at American Family Field is scheduled to commence at 3:10PM ET.

• Who: Cincinnati Reds vs. Milwaukee Brewers
• Date: Sunday, September 28, 2025
• Time: 3:10PM ET/12:10PM PT
• Venue: American Family Field

Dimers' in-depth preview of Sunday's Reds vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Brewers, with a 57% win probability, will likely beat the Reds on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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