Reds vs. Dodgers prediction: Dodgers favored to win Wednesday's MLB matchup [8/27/2025]

MLB action continues on Wednesday at 8:40PM ET as the Cincinnati Reds square off with the Los Angeles Dodgers at Dodger Stadium.

The Dodgers will send Shohei Ohtani (0-1, 4.61 ERA) to the mound, while the Reds have opted for Nick Lodolo (8-6, 3.05 ERA).

Based on the latest simulations, Dimers' advanced MLB model projects the Dodgers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Reds-Dodgers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Dodgers' chance of winning at 62%, with the Reds at 38%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Reds vs. Dodgers predictions page.

Dodgers vs. Reds prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Reds and Dodgers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Dodgers a 62% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 57% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.

Reds vs. Dodgers odds [8/27/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Dodgers
Run Line	+1.5 (-130)	-1.5 (+113)
Moneyline	+160	-181
Total	o7.5 (-119)	u7.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Dodgers picks and best bets

Our model's biggest edge in today's Reds vs. Dodgers matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

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Reds vs. Dodgers game-day updates and essential details

Wednesday's MLB game between the Dodgers and Reds at Dodger Stadium is scheduled to commence at 8:40PM ET.

• Who: Cincinnati Reds vs. Los Angeles Dodgers
• Date: Wednesday, August 27, 2025
• Time: 8:40PM ET/5:40PM PT
• Venue: Dodger Stadium

Dimers.com's in-depth preview of Wednesday's Reds vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Dodgers, with a 62% win probability, will likely beat the Reds on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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