Reds vs. Angels prediction: Angels predicted to win Wednesday's MLB matchup [8/20/2025]

The Los Angeles Angels and Cincinnati Reds are scheduled to meet in MLB action at Angel Stadium on Wednesday, starting at 9:38PM ET.

The Angels will start Yusei Kikuchi (6-8, 3.52 ERA), up against Nick Martinez (10-9, 4.73 ERA) for the Reds.

Based on updated simulations, Dimers' proven MLB model predicts the Angels as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Reds-Angels game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Angels' chance of winning at 56%, with the Reds at 44%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Reds vs. Angels predictions page.

Angels vs. Reds prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Reds and Angels 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Angels a 56% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 62% chance of covering the run line, while the over/under total of 9 runs has a 54% chance of staying under.

Reds vs. Angels odds [8/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Angels
Run Line	+1.5 (-194)	-1.5 (+168)
Moneyline	+108	-120
Total	o9 (+100)	u9 (-118)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Angels picks and best bets

Our model's biggest edge in today's Reds vs. Angels matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Reds vs. Angels game-day updates and essential details

Wednesday's MLB game between the Angels and Reds at Angel Stadium is scheduled to start at 9:38PM ET.

• Who: Cincinnati Reds vs. Los Angeles Angels
• Date: Wednesday, August 20, 2025
• Time: 9:38PM ET/6:38PM PT
• Venue: Angel Stadium

Dimers.com's comprehensive preview of Wednesday's Reds vs. Angels matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Angels picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Angels, with a 56% win probability, will likely beat the Reds on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Angels insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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