Reds vs. Royals Prediction: Kansas City Predicted to Win Wednesday's MLB Matchup [5/28/2025]

MLB action continues on Wednesday at 7:40PM ET as the Cincinnati Reds square off with the Kansas City Royals at Kauffman Stadium.

The Royals will send Noah Cameron (1-1, 0.93 ERA) to the mound, pitting him against Hunter Greene (4-2, 2.54 ERA) for the Reds.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Royals as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Cincinnati-Kansas City game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Royals' chance of winning at 51%, with the Reds at 49%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Reds vs. Royals predictions page.

Royals vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Reds and Royals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Royals a 51% chance of defeating the Reds.

According to our model, the Royals (+1.5) have a 65% chance of covering the run line, while the 8-run over/under has a 53% chance of staying under.

Reds vs. Royals Odds [5/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Royals
Run Line	-1.5 (+150)	+1.5 (-172)
Moneyline	-118	+102
Total	o8 (-102)	u8 (-118)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Royals Picks and Best Bets

Our model's biggest edge in today's Reds vs. Royals matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Reds vs. Royals Game-Day Updates and Essential Details

Wednesday's MLB action between the Royals and Reds at Kauffman Stadium is scheduled to commence at 7:40PM ET.

• Who: Cincinnati Reds vs. Kansas City Royals
• Date: Wednesday, May 28, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Kauffman Stadium

Dimers.com's in-depth preview of Wednesday's Reds vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Kansas City picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Royals, with a 51% win probability, will likely beat the Reds on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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