Reds vs. Cubs Prediction: Cubs Predicted to Win Monday's MLB Matchup [8/4/2025]

The Chicago Cubs and Cincinnati Reds will lock horns in MLB action at Wrigley Field on Monday, starting at 8:05PM ET.

The Cubs will send Michael Soroka (3-8, 4.87 ERA) to the mound, pitting him against Nick Lodolo (8-6, 3.09 ERA) for the Reds.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Cubs as the most likely winner of today's game.

For further insights into Monday's matchup, including best bets and picks, visit our interactive Reds vs. Cubs predictions page.

Cubs vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the result of Monday's MLB matchup between the Reds and Cubs 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Cubs a 57% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 63% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.

Reds vs. Cubs Odds [8/4/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Cubs
Run Line	+1.5 (-190)	-1.5 (+160)
Moneyline	+115	-134
Total	o7.5 (+100)	u7.5 (-122)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Cubs Picks and Best Bets

Our model's strongest edge in today's Reds vs. Cubs matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Reds vs. Cubs Game-Day Updates and Essential Details

Monday's MLB game between the Cubs and Reds at Wrigley Field is scheduled to commence at 8:05PM ET.

• Who: Cincinnati Reds vs. Chicago Cubs
• Date: Monday, August 4, 2025
• Time: 8:05PM ET/5:05PM PT
• Venue: Wrigley Field

Dimers.com's full preview of Monday's Reds vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cubs, with a 57% win probability, will likely beat the Reds on Monday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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