Reds vs. Diamondbacks prediction: Why Cincinnati is favored to win Saturday's MLB matchup [8/23/2025]

The Arizona Diamondbacks will take on the Cincinnati Reds, in what is expected to be a tight MLB game, at Chase Field on Saturday, beginning at 8:10PM ET.

Jalen Beeks (4-1, 4.07 ERA) will start for the Diamondbacks, up against Andrew Abbott (8-3, 2.28 ERA) for the Reds.

Based on the latest simulations, Dimers' proven MLB model predicts the Reds as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Reds vs. Diamondbacks predictions page.

Diamondbacks vs. Reds prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's MLB matchup between the Reds and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Reds a 51% chance of beating the Diamondbacks.

According to our model, the Diamondbacks (+1.5) have a 61% chance of covering the run line, while the over/under total of 9 runs has an equal 50-50 chance of hitting.

Reds vs. Diamondbacks odds [8/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Diamondbacks
Run Line	-1.5 (+140)	+1.5 (-158)
Moneyline	-120	+103
Total	o9 (-108)	u9 (-110)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Diamondbacks picks and best bets

Our model's strongest edge in today's Reds vs. Diamondbacks matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Reds vs. Diamondbacks game-day updates and essential details

Saturday's MLB matchup between the Diamondbacks and Reds at Chase Field is scheduled to start at 8:10PM ET.

• Who: Cincinnati Reds vs. Arizona Diamondbacks
• Date: Saturday, August 23, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Chase Field

Dimers.com's full preview of Saturday's Reds vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Reds vs. Diamondbacks picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 51% win probability, will likely beat the Diamondbacks on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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