Cincinnati Bengals vs. Cleveland Browns early prediction: Expert picks for NFL Week 1, 2025

The Cincinnati Bengals and Cleveland Browns will meet in Week 1 of the NFL season at Huntington Bank Field on Sunday, September 7, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Bengals as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Bengals vs. Browns predictions page.

Cincinnati vs. Cleveland early predictions

Leveraging trusted machine learning and analysis, we have simulated the Bengals vs. Browns game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Bengals 69%, Browns 31%
• Predicted final score: Bengals 26-20 Browns
• Spread: Bengals (-5.5) 50%, Browns (+5.5) 50%
• Total points (47.5): Over 46%, Under 54%

As of August 31, 2025, these Bengals-Browns figures and predictions reflect the latest data and insights available.

Bengals vs. Browns Week 1 details

The NFL Week 1 game between the Browns and Bengals at Huntington Bank Field is scheduled for September 7, 2025.

• Who: Cincinnati Bengals vs. Cleveland Browns
• Date: Sunday, September 7, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Huntington Bank Field

Bengals vs. Browns opening odds

We've researched the best betting odds across America for this Week 1 game, which are listed here:

• Spread: Bengals -5.5 (-105), Browns +5.5 (-108)
• Moneyline: Bengals -225, Browns +200
• Total: Over/Under 47.5 (-110/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Bengals, with a 69% win probability, will likely beat the Browns in Week 1 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bengals vs. Browns matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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