Chiefs vs. Chargers Predictions and Odds - Dec 16, 2021

The Los Angeles Chargers square off with the Kansas City Chiefs in NFL Week 15 action at SoFi Stadium on Thursday, commencing at 8:20 PM EST.

Dimers' best betting picks for Chiefs vs. Chargers, as well as game predictions, best odds and player props, are featured below.

Who will win Chiefs vs. Chargers?

Using cutting-edge computer power and data, Dimers.com has simulated Thursday's Chiefs-Chargers NFL game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Chiefs a 59% chance of defeating the Chargers.

MORE: Chiefs vs. Chargers Simulated 10K Times

Point Spread, Moneyline and Over/Under

The Chargers are +3.5 underdogs versus the Chiefs, with -110 at PointsBet the best odds available.

For the favored Chiefs (-3.5) to cover the spread, DraftKings Sportsbook has the best odds on offer at +100.

DraftKings Sportsbook has the best moneyline odds for the Chargers at +150. That means you can bet $100 to profit $150, earning a total payout of $250, if they win.

Elsewhere, FanDuel Sportsbook has the best moneyline odds for the Chiefs at -168, where you can risk $168 to win $100, for a total payout of $268, if they come out on top.

The Over/Under is set at 54 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the Chargers (+3.5) are a 56% chance of covering the spread, while the Over/Under total of 54 points is a 53% chance of going Under.

MORE: Today's Best Bets for All Major Sports

Best Bets for Chiefs vs. Chargers

• Spread: Chargers +3.5 at -110 with PointsBet (56% probability) 🔥
• Moneyline: Chargers Win at +150 with DraftKings Sportsbook (0.9% edge)
• Over/Under: Under 54 at -110 with BetMGM (53% probability)

If you see a 🔥, that means it's one of Dimers' best bets of the day across all sports.

While the Chiefs are more likely to win the game, according to DimersBOT, taking the Chargers moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges seen here at Dimers.com is crucial to achieving long-term profitability as a sports bettor.

Chiefs vs. Chargers Score Prediction

Dimers.com's predicted final score for Kansas City vs. LA Chargers at SoFi Stadium on Thursday has the Chiefs winning 28-25.

Use our dynamic widget below to view the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Chiefs-Chargers matchup, including pre-game predictions, free betting picks, and live win probabilities.

Chiefs vs. Chargers Player Props

Who will score the first touchdown in Chiefs vs. Chargers? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Chiefs and Chargers, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you discover the best prop bets for Thursday's game.

According to DimersBOT, Kansas City's Tyreek Hill is most likely to score the first TD in Chiefs vs. Chargers.

DimersBOT gives Hill a 12.2% chance of getting in for six first at SoFi Stadium, while the Chiefs WR is a 53.1% chance of scoring an anytime touchdown.

First Touchdown Scorer Probabilities

Kansas City Chiefs

• Tyreek Hill: 12.2% probability
• Travis Kelce: 11.8% probability
• Clyde Edwards-Helaire: 8.4% probability
• Darrel Williams: 5.6% probability
• Mecole Hardman: 4.3% probability

Los Angeles Chargers

• Austin Ekeler: 11.2% probability
• Keenan Allen: 7.4% probability
• Mike Williams: 7.4% probability
• Jared Cook: 4.7% probability
• Justin Herbert: 4.4% probability

Anytime Touchdown Scorer Probabilities

Kansas City Chiefs

• Tyreek Hill: 53.1% probability
• Travis Kelce: 52.5% probability
• Clyde Edwards-Helaire: 41.7% probability
• Darrel Williams: 31.5% probability
• Mecole Hardman: 25.2% probability

Los Angeles Chargers

• Austin Ekeler: 52.1% probability
• Keenan Allen: 38.2% probability
• Mike Williams: 35.5% probability
• Jared Cook: 26.5% probability
• Justin Herbert: 23.8% probability

Projected Box Score

Of the starting quarterbacks, the Chiefs' Patrick Mahomes is projected to have a big game with 293 passing yards and 2.2 passing touchdowns. The Chargers' Justin Herbert is expected to throw for a whopping 295 yards and 2.0 TDs.

Chiefs Starting QB

• Patrick Mahomes: 293 Passing Yards, 2.2 Passing TDs

Chargers Starting QB

• Justin Herbert: 295 Passing Yards, 2.0 Passing TDs

Chiefs Rushing

• Clyde Edwards-Helaire: 47 Rushing Yards, 0.4 TDs
• Darrel Williams: 23 Rushing Yards, 0.2 TDs
• Patrick Mahomes: 19 Rushing Yards, 0.2 TDs

Chargers Rushing

• Austin Ekeler: 55 Rushing Yards, 0.4 TDs
• Justin Jackson: 21 Rushing Yards, 0.1 TDs
• Justin Herbert: 19 Rushing Yards, 0.2 TDs

Chiefs Receiving

• Tyreek Hill: 75 Receiving Yards, 0.7 TDs
• Travis Kelce: 71 Receiving Yards, 0.6 TDs
• Mecole Hardman: 29 Receiving Yards, 0.2 TDs
• Byron Pringle: 27 Receiving Yards, 0.2 TDs
• Darrel Williams: 26 Receiving Yards, 0.2 TDs

Chargers Receiving

• Keenan Allen: 69 Receiving Yards, 0.4 TDs
• Mike Williams: 62 Receiving Yards, 0.4 TDs
• Jared Cook: 42 Receiving Yards, 0.3 TDs
• Austin Ekeler: 35 Receiving Yards, 0.3 TDs
• Jalen Guyton: 22 Receiving Yards, 0.2 TDs

Don't forget, DimersBOT updates often, so check this article for the latest betting analysis ahead of Chiefs vs. Chargers on Thursday December 16, 2021.

Bet $10, Win $200 if Chiefs or Chargers Score a TD

BetMGM, the king of sportsbooks, is offering new users the opportunity to Bet $10, Win $200 if the Chiefs or Chargers score a touchdown on Thursday.

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To claim this promo, join BetMGM via this exclusive link, deposit $10+ and place, as your first real-money bet after opening your account, a single $10 pre-game, moneyline wager on Kansas City vs. LA Chargers.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a partnership with (such as an online sportsbook), we may earn a referral fee.

Chiefs vs. Chargers 2021 Game Info

When do the Chargers play the Chiefs?

• Date: Thursday December 16, 2021
• Time: 8:20 PM EST / 5:20 PM PST
• Venue: SoFi Stadium

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