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White Sox vs. Rays Prediction: Tampa Bay Predicted to Win Monday's MLB Matchup [7/21/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Monday's Chicago White Sox vs Tampa Bay Rays matchup.
MLB action continues on Monday at 7:35PM ET as the Chicago White Sox square off with the Tampa Bay Rays at George M. Steinbrenner Field.
The Rays will have Shane Baz (8-5, 4.17 ERA) as their starting pitcher, while the White Sox have opted for Sean Burke (4-8, 4.36 ERA).
Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Rays as the most likely winner of today's game.
For a closer look at Monday's matchup, including best bets and picks, visit our interactive White Sox vs. Rays predictions page.
Rays vs. White Sox Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Monday's MLB matchup between the White Sox and Rays 10,000 times as part of our MLB predictions coverage.
Our leading predictive model gives the Rays a 67% chance of beating the White Sox.
According to our model, the White Sox (+1.5) have a 52% chance of covering the run line, while the over/under total of 9 runs has a 55% chance of staying under.
White Sox vs. Rays Odds [7/21/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | White Sox | Rays |
|---|---|---|
| Run Line | +1.5 (-109) | -1.5 (-110) |
| Moneyline | +180 | -215 |
| Total | o9 (-102) | u9 (-118) |
All odds are correct at the time of publication and are subject to change.
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White Sox vs. Rays Picks and Best Bets
Our model's biggest edge in today's White Sox vs. Rays matchup is on the run line.
Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets
Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.
White Sox vs. Rays Game-Day Updates and Essential Details
Monday's MLB matchup between the Rays and White Sox at George M. Steinbrenner Field is scheduled to commence at 7:35PM ET.
- Who: Chicago White Sox vs. Tampa Bay Rays
- Date: Monday, July 21, 2025
- Time: 7:35PM ET/4:35PM PT
- Venue: George M. Steinbrenner Field
Dimers.com's in-depth preview of Monday's White Sox vs. Rays matchup includes our prediction, picks and the latest betting odds.
Before making any White Sox vs. Rays picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Rays, with a 67% win probability, will likely beat the White Sox on Monday.
AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Rays insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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