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White Sox vs. Mariners Prediction: Seattle Predicted to Win Wednesday's MLB Matchup [8/6/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Wednesday's Chicago White Sox vs Seattle Mariners matchup.
The Seattle Mariners and Chicago whitesox will lock horns in MLB action at T-Mobile Park on Wednesday, starting at 9:40PM ET.
The Mariners will send George Kirby (6-5, 4.12 ERA) to the mound, up against Jonathan Cannon (4-8, 4.77 ERA) for the White Sox.
Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's White Sox-Mariners game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"With the latest updates and numerous other variables, we estimate the Mariners' chance of winning at 70%, with the White Sox at 30%."
For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive White Sox vs. Mariners predictions page.
Mariners vs. White Sox Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's MLB game between the White Sox and Mariners 10,000 times as part of our MLB predictions coverage.
Our leading predictive model gives the Mariners a 70% chance of beating the White Sox.
According to our model, the Mariners (-1.5) have a 51% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.
White Sox vs. Mariners Odds [8/6/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | White Sox | Mariners |
|---|---|---|
| Run Line | +1.5 (+108) | -1.5 (-120) |
| Moneyline | +220 | -270 |
| Total | o7.5 (-105) | u7.5 (-114) |
All odds are correct at the time of publication and are subject to change.
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White Sox vs. Mariners Picks and Best Bets
Our model's biggest edge in today's White Sox vs. Mariners matchup is on the total.
Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets
Calling Our Shot produces daily MLB betting content, including the best bets featured below.
White Sox vs. Mariners Game-Day Updates and Essential Details
Wednesday's MLB game between the Mariners and White Sox at T-Mobile Park is scheduled to start at 9:40PM ET.
- Who: Chicago White Sox vs. Seattle Mariners
- Date: Wednesday, August 6, 2025
- Time: 9:40PM ET/6:40PM PT
- Venue: T-Mobile Park
Dimers.com's full preview of Wednesday's White Sox vs. Mariners matchup includes our prediction, picks and the latest betting odds.
Before making any White Sox vs. Mariners picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Mariners, with a 70% win probability, will likely beat the White Sox on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on MLB
Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most up-to-date projections for the World Series, American League, National League and each division.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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