White Sox vs. Pirates Prediction: Pittsburgh Predicted to Win Sunday's MLB Matchup [7/20/2025]

The Pittsburgh Pirates will square off with the Chicago White Sox in MLB action at PNC Park on Sunday, commencing at 1:35PM ET.

The Pirates will send Andrew Heaney (4-8, 4.59 ERA) to the mound, while the White Sox are going with Aaron Civale (1-6, 5.30 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Pirates as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's White Sox-Pirates game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Pirates with a win probability of 59%, while the White Sox have 41%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive White Sox vs. Pirates predictions page.

Pirates vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's MLB matchup between the White Sox and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Pirates a 59% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 60% chance of covering the run line, while the 9.5-run over/under has a 57% chance of staying under.

White Sox vs. Pirates Odds [7/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Pirates
Run Line	+1.5 (-166)	-1.5 (+150)
Moneyline	+121	-142
Total	o9.5 (+102)	u9.5 (-120)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Pirates Picks and Best Bets

Our model's biggest edge in today's White Sox vs. Pirates matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

White Sox vs. Pirates Game-Day Updates and Essential Details

Sunday's MLB action between the Pirates and White Sox at PNC Park is scheduled to start at 1:35PM ET.

• Who: Chicago White Sox vs. Pittsburgh Pirates
• Date: Sunday, July 20, 2025
• Time: 1:35PM ET/10:35AM PT
• Venue: PNC Park

Dimers.com's full preview of Sunday's White Sox vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any White Sox vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 59% win probability, will likely beat the White Sox on Sunday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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